Issue 6, 2013

Catalyst-free, one-pot three-component 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes

Abstract

An one-pot efficient diastereoselective 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes has been developed. Catalyst-free conditions, facile procedure and high yields of the polysubstituted benzopyrano[3,4-c]-pyrrolidines are the salient features of this methodology.

Graphical abstract: Catalyst-free, one-pot three-component 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes

Supplementary files

Article information

Article type
Paper
Submitted
23 Nov 2012
Accepted
29 Nov 2012
First published
29 Nov 2012

RSC Adv., 2013,3, 1970-1975

Catalyst-free, one-pot three-component 1,3-dipolar cycloaddition of diethyl 2-aminomalonate, benzaldehydes and 3-nitro-2H-chromenes

Y. Jia and D. Du, RSC Adv., 2013, 3, 1970 DOI: 10.1039/C2RA23035F

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