Issue 3, 2013
From the journal:

RSC Advances

High resolution imaging of mitochondrial membranes by in situ atomic force microscopy‡

Yongmei Tian,‡ac   Jiahan Li,‡b   Mingjun Cai,a   Weidong Zhao,ac   Haijiao Xu,a   Yi Liu*b  and  Hongda Wang*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P.R. China
E-mail: hdwang@ciac.jl.cn

b State Key Laboratory of Virology, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P.R China
E-mail: yiliuchem@whu.edu.cn

c University of Chinese Academy of Sciences, Beijing 100049, P.R. China

Abstract

We used in situ atomic force microscope (AFM) to explore the exquisite structure of mitochondrial membranes under quasi-native conditions. The outer surface of the mitochondrial membrane is slightly rough and protein-embedded inside, while the inner mitochondrial membrane is smooth in the intermembrane space surface and protein-covered on the matrix side.

Graphical abstract: High resolution imaging of mitochondrial membranes by in situ atomic force microscopy

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Article information

DOI
https://doi.org/10.1039/C2RA22166G
Article type
Communication
Submitted
14 Sep 2012
Accepted
12 Nov 2012
First published
13 Nov 2012

RSC Adv., 2013,3, 708-712

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High resolution imaging of mitochondrial membranes by in situ atomic force microscopy

Y. Tian, J. Li, M. Cai, W. Zhao, H. Xu, Y. Liu and H. Wang, RSC Adv., 2013, 3, 708 DOI: 10.1039/C2RA22166G

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