Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones†
Abstract
Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3′-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).