Issue 39, 2013

Efficient synthesis of trifluoromethylated cyclopentadienes/fulvenes/norbornenes from divinyl ketones

Abstract

The synthetic methods of trifluoromethylated cyclopentadienes/fulvenes/norbornenes have been developed using 3-CF3-1,4-dien-3-ols as the synthons, which can be easily prepared by the regiospecific 1,2-addition of the Ruppert–Prakash reagent (TMSCF3) to divinyl ketones. All the reactions are carried out under mild, metal-free conditions to afford the corresponding products in high to excellent yields.

Graphical abstract: Efficient synthesis of trifluoromethylated cyclopentadienes/fulvenes/norbornenes from divinyl ketones

Supplementary files

Article information

Article type
Communication
Submitted
08 Jul 2013
Accepted
16 Aug 2013
First published
03 Sep 2013

Org. Biomol. Chem., 2013,11, 6703-6706

Efficient synthesis of trifluoromethylated cyclopentadienes/fulvenes/norbornenes from divinyl ketones

X. Liu, X. Xu, L. Pan, Q. Zhang and Q. Liu, Org. Biomol. Chem., 2013, 11, 6703 DOI: 10.1039/C3OB41400K

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