Issue 36, 2013

AgOTf-catalyzed reactions of naphthols/substituted phenols with 2-hydroxychalcones: facile synthesis of di-aromatic ring-fused [3.3.1]bicyclic compounds

Abstract

A simple and efficient method for the synthesis of functionalized di-aromatic ring-fused 2,8-dioxabicyclo[3.3.1]nonane derivatives catalyzed by silver triflate from easily available 2-hydroxychalcones and naphthols/substituted phenols is described. Two six-membered cycles were formed in a one-pot operation. This reaction was probably achieved via a Friedel–Crafts alkylation/bicyclization domino process.

Graphical abstract: AgOTf-catalyzed reactions of naphthols/substituted phenols with 2-hydroxychalcones: facile synthesis of di-aromatic ring-fused [3.3.1]bicyclic compounds

Supplementary files

Article information

Article type
Paper
Submitted
26 Apr 2013
Accepted
11 Jul 2013
First published
12 Jul 2013

Org. Biomol. Chem., 2013,11, 6029-6035

AgOTf-catalyzed reactions of naphthols/substituted phenols with 2-hydroxychalcones: facile synthesis of di-aromatic ring-fused [3.3.1]bicyclic compounds

Y. Rao and G. Yin, Org. Biomol. Chem., 2013, 11, 6029 DOI: 10.1039/C3OB40860D

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