Issue 21, 2013
From the journal:

Organic & Biomolecular Chemistry

Tandem iodine-mediated oxidations of tetrahydro-β-carbolines: total synthesis of eudistomins Y1–Y7†

Joseph D. Panaresea  and  Stephen P. Waters*a  

* Corresponding authors

a Department of Chemistry, The University of Vermont, 82 University Place, Burlington, VT, USA
E-mail: Stephen.Waters@uvm.edu
Fax: +1 802-656-8705
Tel: +1 802-656-0274

Abstract

An efficient iodine-mediated oxidation of tetrahydro-β-carbolines is described to yield aromatic β-carboline products with tandem C–H oxidation. The utility of the method was demonstrated in total syntheses of the alkaloids eudistomins Y1–Y7.

Graphical abstract: Tandem iodine-mediated oxidations of tetrahydro-β-carbolines: total synthesis of eudistomins Y1–Y7

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Article information

DOI
https://doi.org/10.1039/C3OB40661J
Article type
Communication
Submitted
03 Apr 2013
Accepted
15 Apr 2013
First published
16 Apr 2013

Org. Biomol. Chem., 2013,11, 3428-3431

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Tandem iodine-mediated oxidations of tetrahydro-β-carbolines: total synthesis of eudistomins Y1–Y7

J. D. Panarese and S. P. Waters, Org. Biomol. Chem., 2013, 11, 3428 DOI: 10.1039/C3OB40661J

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