Issue 21, 2013
From the journal:

Nanoscale

pH-responsive gold nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor delivery†

Jutaek Nam,a   Yeong Su Ha,b   Sekyu Hwang,a   Woonghee Lee,b   Jaejung Song,c   Jeongsoo Yoob  and  Sungjee Kim*ac  

* Corresponding authors

a Department of Chemistry, Pohang University of Science & Technology (POSTECH), San 31, Hyojadong, Namgu, Pohang 790-784, South Korea
E-mail: Sungjee@postech.ac.kr
Fax: +82-279-1498
Tel: +82-279-2108

b Department of Molecular Medicine, School of Medicine, Kyungpook National University, Dongin-dong, Joong-gu, Daegu 700-422, South Korea

c School of Interdisciplinary Bioscience and Bioengineering, POSTECH, South Korea

Abstract

We report a pH-responsive gold nanoparticles-in-liposome hybrid nanostructure, which effectively combines the pH-responsive assembly and surface plasmon property changes of ‘smart’ gold nanoparticles and enhanced systemic circulation and tumor accumulation of the PEG-grafted liposomes.

Graphical abstract: pH-responsive gold nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor delivery

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Article information

DOI
https://doi.org/10.1039/C3NR03698G
Article type
Communication
Submitted
18 Jul 2013
Accepted
28 Aug 2013
First published
29 Aug 2013

Nanoscale, 2013,5, 10175-10178

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pH-responsive gold nanoparticles-in-liposome hybrid nanostructures for enhanced systemic tumor delivery

J. Nam, Y. S. Ha, S. Hwang, W. Lee, J. Song, J. Yoo and S. Kim, Nanoscale, 2013, 5, 10175 DOI: 10.1039/C3NR03698G

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