Issue 8, 2013

A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

Abstract

The interaction forces between carbohydrates and lectins were investigated by single-molecule force spectroscopy on both cancer and normal cells. The binding kinetics was also studied, which shows that the carbohydrate–lectin complex on cancer cells is less stable than that on normal cells.

Graphical abstract: A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

Supplementary files

Article information

Article type
Communication
Submitted
31 Jan 2013
Accepted
25 Feb 2013
First published
26 Feb 2013

Nanoscale, 2013,5, 3226-3229

A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

W. Zhao, M. Cai, H. Xu, J. Jiang and H. Wang, Nanoscale, 2013, 5, 3226 DOI: 10.1039/C3NR00553D

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