Jump to main content
Jump to site search
SCHEDULED MAINTENANCE Close the message box

Maintenance work is planned for Monday 16 August 2021 from 07:00 to 23:59 (BST).

Website performance may be temporarily affected and you may not be able to access some PDFs or images. If this does happen, refreshing your web browser should resolve the issue. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 5, 2013

Perspectives on natural product epigenetic modulators in chemical biology and medicine

Author affiliations

Abstract

Covering: up to the end of 2012

Epigenetic processes are complex regulatory transcriptional pathways that underpin fundamental physiology and are implicated in the aetiology of many diseases. Small molecule modulators of key epigenetic targets will be central in the study of these intricate networks as well as providing highly useful start points for drug discovery efforts. In this review we will give our perspective on the current status of natural product epigenetic modulators, highlighting the limitations, challenges and opportunities for currently identified molecules, as well as potential strategies for novel compound discovery moving forward.

Graphical abstract: Perspectives on natural product epigenetic modulators in chemical biology and medicine

Article information


Submitted
27 Sep 2012
First published
11 Feb 2013

Nat. Prod. Rep., 2013,30, 605-624
Article type
Review Article

Perspectives on natural product epigenetic modulators in chemical biology and medicine

F. L. Cherblanc, R. W. M. Davidson, P. Di Fruscia, N. Srimongkolpithak and M. J. Fuchter, Nat. Prod. Rep., 2013, 30, 605 DOI: 10.1039/C3NP20097C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements