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Issue 2, 2013
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Anticancer steroids: linking natural and semi-synthetic compounds

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Abstract

Covering: up to 2012

Steroids, a widespread class of natural organic compounds occurring in animals, plants and fungi, have shown great therapeutic value for a broad array of pathologies. The present overview is focused on the anticancer activity of steroids, which is very representative of a rich structural molecular diversity and ability to interact with various biological targets and pathways. This review encompasses the most relevant discoveries on steroid anticancer drugs and leads through the last decade and comprises 668 references.

Graphical abstract: Anticancer steroids: linking natural and semi-synthetic compounds

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Article information


Submitted
31 Jul 2012
First published
14 Nov 2012

Nat. Prod. Rep., 2013,30, 324-374
Article type
Review Article

Anticancer steroids: linking natural and semi-synthetic compounds

J. A. R. Salvador, J. F. S. Carvalho, M. A. C. Neves, S. M. Silvestre, A. J. Leitão, M. M. C. Silva and M. L. Sá e Melo, Nat. Prod. Rep., 2013, 30, 324
DOI: 10.1039/C2NP20082A

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