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Issue 5, 2013
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Friedlander synthesis of novel benzopyranopyridines in the presence of chitosan as heterogeneous, efficient and biodegradable catalyst under solvent-free conditions

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Abstract

Efficient synthesis of benzopyrano[4,3-b]pyridine derivatives was achieved from 4-amino-3-formylcoumarin and different active methylene compounds under solvent-free thermal heating at 80 °C via Friedlander condensation in the presence of chitosan as heterogeneous, basic green catalyst. The present methodology is a novel green approach to benzopyranopyridine. It offers several advantages such as shorter reaction time, mild reaction conditions, simple operational procedure, use of recyclable and biodegradable catalyst.

Graphical abstract: Friedlander synthesis of novel benzopyranopyridines in the presence of chitosan as heterogeneous, efficient and biodegradable catalyst under solvent-free conditions

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Publication details

The article was received on 16 Jan 2013, accepted on 05 Mar 2013 and first published on 06 Mar 2013


Article type: Paper
DOI: 10.1039/C3NJ00069A
Citation: New J. Chem., 2013,37, 1595-1602
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    Friedlander synthesis of novel benzopyranopyridines in the presence of chitosan as heterogeneous, efficient and biodegradable catalyst under solvent-free conditions

    Z. N. Siddiqui and K. Khan, New J. Chem., 2013, 37, 1595
    DOI: 10.1039/C3NJ00069A

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