Issue 6, 2013
From the journal:

New Journal of Chemistry

Direct synthesis of pyrrolesvia1,3-dipolar cycloaddition of azomethine ylides with ynones†

Zheng Wang,a   Ying Shi,a   Xiaoyan Luo,a   De-Man Hanb  and  Wei-Ping Deng*ac  

* Corresponding authors

a School of Pharmacy and Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China
E-mail: weiping_deng@ecust.edu.cn

b Department of Chemistry, Taizhou University, 605 Dongfang Road, Linhai 317000, China

c Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 LingLing Road, Shanghai 200032, China

Abstract

A direct and facile synthesis of multi-substituted pyrroles via AgOAc-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with ynones is developed, providing the corresponding adducts in moderate to high yields (up to 89%).

Graphical abstract: Direct synthesis of pyrroles via 1,3-dipolar cycloaddition of azomethine ylides with ynones

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Article information

DOI
https://doi.org/10.1039/C3NJ00067B
Article type
Paper
Submitted
16 Jan 2013
Accepted
07 Mar 2013
First published
08 Mar 2013

New J. Chem., 2013,37, 1742-1745

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Direct synthesis of pyrroles via 1,3-dipolar cycloaddition of azomethine ylides with ynones

Z. Wang, Y. Shi, X. Luo, D. Han and W. Deng, New J. Chem., 2013, 37, 1742 DOI: 10.1039/C3NJ00067B

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