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Issue 5, 2013
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Synthesis and trypanocidal action of new adamantane substituted imidazolines

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Abstract

Introduction of the hydrophobic substituents cyclopentyl, cyclohexyl and phenyl into adamantane imidazolines was accomplished with the synthesis of compounds 4. Members of this series were found to display a range of activities against bloodstream forms of Trypanosoma brucei.

Graphical abstract: Synthesis and trypanocidal action of new adamantane substituted imidazolines

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Publication details

The article was received on 13 Mar 2013, accepted on 31 Mar 2013 and first published on 02 Apr 2013


Article type: Concise Article
DOI: 10.1039/C3MD00081H
Med. Chem. Commun., 2013,4, 856-859

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    Synthesis and trypanocidal action of new adamantane substituted imidazolines

    A. Koperniku, I. Papanastasiou, G. B. Foscolos, A. Tsotinis, M. C. Taylor and J. M. Kelly, Med. Chem. Commun., 2013, 4, 856
    DOI: 10.1039/C3MD00081H

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