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Issue 12, 2013
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Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations

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Abstract

We describe a generic microfluidic interface design that allows the connection of microfluidic chips to established industrial liquid handling stations (LHS). A molding tool has been designed that allows fabrication of low-cost disposable polydimethylsiloxane (PDMS) chips with interfaces that provide convenient and reversible connection of the microfluidic chip to industrial LHS. The concept allows complete freedom of design for the microfluidic chip itself. In this setup all peripheral fluidic components (such as valves and pumps) usually required for microfluidic experiments are provided by the LHS. Experiments (including readout) can be carried out fully automated using the hardware and software provided by LHS manufacturer. Our approach uses a chip interface that is compatible with widely used and industrially established LHS which is a significant advancement towards near-industrial experimental design in microfluidics and will greatly facilitate the acceptance and translation of microfluidics technology in industry.

Graphical abstract: Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations

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Publication details

The article was received on 08 Jan 2013, accepted on 28 Mar 2013 and first published on 03 Apr 2013


Article type: Paper
DOI: 10.1039/C3LC00042G
Citation: Lab Chip, 2013,13, 2337-2343
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    Microfluidics on liquid handling stations (μF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations

    A. Waldbaur, J. Kittelmann, C. P. Radtke, J. Hubbuch and B. E. Rapp, Lab Chip, 2013, 13, 2337
    DOI: 10.1039/C3LC00042G

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