Jump to main content
Jump to site search

Issue 11, 2013
Previous Article Next Article

Development of a robust reagent for the two-carbon homologation of aldehydes to (E)-α,β-unsaturated aldehydes in water

Author affiliations

Abstract

Synthesis of a new pinacolacetal-phosphonium salt and its reaction with aldehydes to give homologated acetals and two-carbon homologated unsaturated aldehydes is presented. The chemistry takes place in water under mild conditions and the sequence can be performed in one-flask operation.

Graphical abstract: Development of a robust reagent for the two-carbon homologation of aldehydes to (E)-α,β-unsaturated aldehydes in water

Back to tab navigation

Supplementary files

Article information


Submitted
11 Jul 2013
Accepted
09 Sep 2013
First published
09 Sep 2013

Green Chem., 2013,15, 3146-3149
Article type
Communication

Development of a robust reagent for the two-carbon homologation of aldehydes to (E)-α,β-unsaturated aldehydes in water

J. McNulty, C. Zepeda-Velázquez and D. McLeod, Green Chem., 2013, 15, 3146
DOI: 10.1039/C3GC41383G

Social activity

Search articles by author

Spotlight

Advertisements