Synthesis, characterization and biodistribution of new fatty acids conjugates bearing N,N,N-donors incorporated [99mTc/Re(CO)3]+
Abstract
[99mTc(CO)3]+-6-[N-(2-dipicolyl)amino]hexanoic acid (1a) and [99mTc(CO)3]+-11-[N-(2-dipicolyl)amino]undecanoic acid (1b) were prepared by incorporating [99mTc-(CO)3]+ into 6-[N-(2-dipicolyl)amino]hexanoic acid and 11-[N-(2-dipicolyl)amino]undecanoic acid, respectively. The overall radiochemical yield of 1a and 1b was from 79.7% to 91.3% and radiochemical purity after HPLC