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Issue 1, 2013
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Laccase—a natural source for the synthesis of benzofuro[2,3-c]pyrazolin-5-ones

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Abstract

Enzymatic oxidation of catechols/hydroquinones in the presence of pyrazolin-5-ones as a nucleophile in aqueous solution has been investigated in detail by applying laccase as a catalyst. This is the first report for the enzymatic synthesis of a novel series of compounds. We derived some new compounds with the catechol/hydroquinone ring in moderate yields based on enzymatic synthesis in an environmentally benign aqueous solution. These types of reactions represent a milestone along the path of future sustainable green chemistry.

Graphical abstract: Laccase—a natural source for the synthesis of benzofuro[2,3-c]pyrazolin-5-ones

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Article information


Submitted
30 Jun 2012
Accepted
22 Aug 2012
First published
14 Sep 2012

Catal. Sci. Technol., 2013,3, 230-234
Article type
Paper

Laccase—a natural source for the synthesis of benzofuro[2,3-c]pyrazolin-5-ones

M. Kidwai, A. Jain, A. Sharma and R. C. Kuhad, Catal. Sci. Technol., 2013, 3, 230
DOI: 10.1039/C2CY20452E

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