Issue 20, 2013
From the journal:

CrystEngComm

Cocrystals of gabapentin with C-alkylresorcin[4]arenes†

Harshita Kumari,a   Jin Zhang,a   Loredana Erra,b   Leonard J. Barbour,*c   Carol A. Deakyne*a  and  Jerry L. Atwood*a  

* Corresponding authors

a Department of Chemistry, University of Missouri-Columbia, 601 S. College Avenue, Columbia, MO 65211, USA
E-mail: AtwoodJ@missouri.edu, DeakyneC@missouri.edu
Fax: +1 573 882 2754
Tel: +1 573 882 8374

b European Radiation Synchrotron Facility, 6 Rue Jules Horowitz, 38000 Grenoble, France
Tel: +33 4 76 88 20 00

c Department of Chemistry, University of Stellenbosch, 7600 Stellenbosch, South Africa
E-mail: ljb@sun.ac.za
Fax: +27 (0)21 808 3849
Tel: +27 (0)21 808 3335

Abstract

The synthesis of cocrystals of gabapentin (GBP) with resorcin[4]arenes (RsCn) with different tail lengths, C-hexylresorcin[4]arene (RsC6) and C-propylresorcin[4]arene (RsC3), is reported. The structural elucidations of the two cocrystals show differences in packing arrangements and host–guest interactions.

Graphical abstract: Cocrystals of gabapentin with C-alkylresorcin[4]arenes

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Article information

DOI
https://doi.org/10.1039/C3CE40441B
Article type
Communication
Submitted
12 Mar 2013
Accepted
06 Apr 2013
First published
08 Apr 2013

CrystEngComm, 2013,15, 4045-4048

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Cocrystals of gabapentin with C-alkylresorcin[4]arenes

H. Kumari, J. Zhang, L. Erra, L. J. Barbour, C. A. Deakyne and J. L. Atwood, CrystEngComm, 2013, 15, 4045 DOI: 10.1039/C3CE40441B

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