Issue 7, 2013
From the journal:

CrystEngComm

Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion†

Judit Galcera,*ab   Tomislav Friščić,b   Elies Molinsa  and  William Jonesb  

* Corresponding authors

a Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus de la UAB, 08193 Bellaterra, Spain
E-mail: judit.galcera@gmail.com

b Department of Chemistry, University of Cambridge, Lensfield Road, CB21EW, Cambridge, UK
E-mail: jg544@cam.ac.uk

Abstract

We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.

Graphical abstract: Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

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Article information

DOI
https://doi.org/10.1039/C2CE26791H
Article type
Paper
Submitted
31 Oct 2012
Accepted
29 Nov 2012
First published
29 Nov 2012

CrystEngComm, 2013,15, 1332-1338

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Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

J. Galcera, T. Friščić, E. Molins and W. Jones, CrystEngComm, 2013, 15, 1332 DOI: 10.1039/C2CE26791H

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