Water wires in the nanoporous form II of carbamazepine: a single-crystal X-ray diffraction analysis

Abstract

We report the crystal structure of a new water wire encapsulated inside the channels formed by the hydrophobic aromatic surfaces of carbamazepine. This new example of a water chain increases the scarce collection of structural data in this field and contributes to the understanding of the role of water chains in the stabilization of certain packing motifs.