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Issue 72, 2013
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The G-triplex DNA could function as a new variety of DNA peroxidase

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Abstract

This study is the first to investigate the interactions of hemin with a G-triplex DNA of T1 using different DNA binding assays. The low intrinsic peroxidatic activity of hemin could be significantly enhanced using T1. Furthermore, much decreased oxidation enhancement by T2 or T3 with one key guanine mutation was observed, and the observed peroxidatic activity of T1 should be directly due to the G-triplex complexed with hemin.

Graphical abstract: The G-triplex DNA could function as a new variety of DNA peroxidase

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Publication details

The article was received on 30 May 2013, accepted on 25 Jun 2013 and first published on 26 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC44075C
Citation: Chem. Commun., 2013,49, 7920-7922
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    The G-triplex DNA could function as a new variety of DNA peroxidase

    S. Wang, B. Fu, S. Peng, X. Zhang, T. Tian and X. Zhou, Chem. Commun., 2013, 49, 7920
    DOI: 10.1039/C3CC44075C

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