Issue 94, 2013
From the journal:

Chemical Communications

Mitochondria-specific phosphorescent imaging and tracking in living cells with an AIPE-active iridium(iii) complex†

Yu Chen,‡a   Liping Qiao,‡a   Bole Yu,a   Guanying Li,a   Chunyuan Liu,b   Liangnian Jia  and  Hui Chao*a  

* Corresponding authors

a MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, State Key Laboratory of Optoelectronic Materials and Technologies, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, P. R. China
E-mail: ceschh@mail.sysu.edu.cn

b Department of Chemistry, Jinan University, Guangzhou 510632, P. R. China

Abstract

An AIPE-active iridium(III) complex was found to possess high specificity for mitochondria, superior photostability, low cytotoxicity, and high resistance to the loss of mitochondrial membrane potential. Thus, this complex can be used for mitochondrial imaging and tracking in living cells.

Graphical abstract: Mitochondria-specific phosphorescent imaging and tracking in living cells with an AIPE-active iridium(iii) complex

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Article information

DOI
https://doi.org/10.1039/C3CC46957C
Article type
Communication
Submitted
11 Sep 2013
Accepted
08 Oct 2013
First published
08 Oct 2013

Chem. Commun., 2013,49, 11095-11097

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Mitochondria-specific phosphorescent imaging and tracking in living cells with an AIPE-active iridium(III) complex

Y. Chen, L. Qiao, B. Yu, G. Li, C. Liu, L. Ji and H. Chao, Chem. Commun., 2013, 49, 11095 DOI: 10.1039/C3CC46957C

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