Issue 84, 2013
From the journal:

Chemical Communications

A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector†

Ruijiao Dong,a   Yue Su,*a   Songrui Yu,a   Yongfeng Zhou,a   Yunfeng Lu*b  and  Xinyuan Zhu*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240 Shanghai, People's Republic of China
E-mail: yuesu@sjtu.edu.cn, xyzhu@sjtu.edu.cn
Tel: +86-21-34203400

b Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California 90095, USA
E-mail: luucla@ucla.edu

Abstract

A novel class of redox-responsive cationic supramolecular polymer with effective DNA condensation ability and H2O2-induced DNA release behavior has been successfully constructed from small molecules. This supramolecular polymer can be used in vitro as a promising nonviral vector for gene therapy.

Graphical abstract: A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector

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Article information

DOI
https://doi.org/10.1039/C3CC46123H
Article type
Communication
Submitted
11 Aug 2013
Accepted
29 Aug 2013
First published
30 Aug 2013

Chem. Commun., 2013,49, 9845-9847

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A redox-responsive cationic supramolecular polymer constructed from small molecules as a promising gene vector

R. Dong, Y. Su, S. Yu, Y. Zhou, Y. Lu and X. Zhu, Chem. Commun., 2013, 49, 9845 DOI: 10.1039/C3CC46123H

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