Silver-catalyzed oxidative coupling/cyclization of acrylamides with 1,3-dicarbonyl compounds†
Abstract
An efficient silver-catalyzed oxidative cyclization of acrylamides with 1,3-dicarbonyl compounds is described. It proceeds through a tandem radical addition/cyclization process, in which two new C–C bonds were formed. Furthermore, the same concept can also be extended to the reaction of easily available ketones and acrylamides.
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