Issue 83, 2013
From the journal:

Chemical Communications

Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization†

Xiaolong Zhang,a   Mark R. Battiga  and  Yong Wang*a  

* Corresponding authors

a Department of Bioengineering, College of Engineering, The Pennsylvania State University, University Park, PA 16802-6804, USA
E-mail: yxwbio@engr.psu.edu
Fax: +1-814-863-0490
Tel: +1-814-865-6867

Abstract

Reversible DNA hybridization can be used as a new mechanism to control the sustained and triggered release of therapeutic oligonucleotides from hydrogels.

Graphical abstract: Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization

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Article information

DOI
https://doi.org/10.1039/C3CC45594G
Article type
Communication
Submitted
23 Jul 2013
Accepted
21 Aug 2013
First published
21 Aug 2013

Chem. Commun., 2013,49, 9600-9602

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Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization

X. Zhang, M. R. Battig and Y. Wang, Chem. Commun., 2013, 49, 9600 DOI: 10.1039/C3CC45594G

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