Issue 82, 2013
From the journal:

Chemical Communications

Fluorescence turn-on detection of a protein using cytochrome c as a quencher†

Dongli Liao,‡ab   Jian Chen,‡ab   Wenying Li,‡ab   Qingfeng Zhang,ab   Fangyuan Wang,ab   Yongxin Liab  and  Cong Yu*ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China

b University of the Chinese Academy of Sciences, Beijing 100049, P. R. China
E-mail: congyu@ciac.ac.cn
Fax: +86-431-8526-2710

Abstract

A new approach for the sensitive and selective sensing of a protein has been developed. Cytochrome c could quench the fluorescence of a fluorophore labeled aptamer efficiently. The specific binding between the aptamer and the target protein resulted in a turn-on emission signal, which could be used for protein quantification.

Graphical abstract: Fluorescence turn-on detection of a protein using cytochrome c as a quencher

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Article information

DOI
https://doi.org/10.1039/C3CC43985B
Article type
Communication
Submitted
27 May 2013
Accepted
12 Aug 2013
First published
12 Aug 2013

Chem. Commun., 2013,49, 9458-9460

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Fluorescence turn-on detection of a protein using cytochrome c as a quencher

D. Liao, J. Chen, W. Li, Q. Zhang, F. Wang, Y. Li and C. Yu, Chem. Commun., 2013, 49, 9458 DOI: 10.1039/C3CC43985B

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