Issue 66, 2013
From the journal:

Chemical Communications

A difunctional DNA–AuNP dendrimer coupling DNAzyme with intercalators for femtomolar detection of nucleic acids†

Mingdi Xu,a   Junyang Zhuang,a   Xian Chen,*a   Guonan Chena  and  Dianping Tang*a  

* Corresponding authors

a Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, P.R. China
E-mail: dianping.tang@fzu.edu.cn
Fax: +86 591 22866135
Tel: +86 591 22866125

Abstract

A novel difunctional DNA–nanogold (AuNP) dendrimer with a hemin–G-quadruplex was for the first time utilized as the nanotag for the in situ amplified electronic signal for nucleic acid detection by coupling high-efficiency DNAzyme with the intercalated methylene blue (MB).

Graphical abstract: A difunctional DNA–AuNP dendrimer coupling DNAzyme with intercalators for femtomolar detection of nucleic acids

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Article information

DOI
https://doi.org/10.1039/C3CC43205J
Article type
Communication
Submitted
01 May 2013
Accepted
22 Jun 2013
First published
24 Jun 2013

Chem. Commun., 2013,49, 7304-7306

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A difunctional DNA–AuNP dendrimer coupling DNAzyme with intercalators for femtomolar detection of nucleic acids

M. Xu, J. Zhuang, X. Chen, G. Chen and D. Tang, Chem. Commun., 2013, 49, 7304 DOI: 10.1039/C3CC43205J

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