Issue 48, 2013
From the journal:

Chemical Communications

Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor†

Zhenzhen Lv,ab   Jinchuan Liu,a   Yu Zhou,a   Zheng Guan,a   Shuming Yang,a   Cheng Lib  and  Ailiang Chen*a  

* Corresponding authors

a Institute of Quality Standards and Testing Technology for Agro-products, Key Laboratory of Agro-product Quality and Safety, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture, Beijing, P.R. China
E-mail: ailiang.chen@gmail.com
Tel: +86 10 82106557

b College of Food Science, Sichuan Agricultural University, Ya'an, China

Abstract

A facile and universal aptamer-based label-free approach for highly selective and sensitive fluorescence detection of a broad range of targets including small molecules, inorganic ions and proteins was developed by using PicoGreen to transduce the fluorescent signal of the double stranded DNA duplex formed between a free aptamer and its complementary strand.

Graphical abstract: Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor

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Article information

DOI
https://doi.org/10.1039/C3CC42801J
Article type
Communication
Submitted
16 Apr 2013
Accepted
24 Apr 2013
First published
25 Apr 2013

Chem. Commun., 2013,49, 5465-5467

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Highly sensitive fluorescent detection of small molecules, ions, and proteins using a universal label-free aptasensor

Z. Lv, J. Liu, Y. Zhou, Z. Guan, S. Yang, C. Li and A. Chen, Chem. Commun., 2013, 49, 5465 DOI: 10.1039/C3CC42801J

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