Issue 46, 2013
From the journal:

Chemical Communications

Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors†

Koichiro Hayashi,*a   Michihiro Nakamura,a   Hirokazu Miki,b   Shuji Ozaki,c   Masahiro Abe,d   Toshio Matsumotod  and  Kazunori Ishimuraa  

* Corresponding authors

a Department of Anatomy and Cell Biology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, Japan
E-mail: khayashi@basic.med.tokushima-u.ac.jp

b Division of Transfusion Medicine, Tokushima University Hospital, 2-50-1 Kuramoto-cho, Tokushima, Japan

c Department of Internal Medicine, Tokushima Prefectural Central Hospital, 1-10-3 Kuramoto-cho, Tokushima, Japan

d Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Medical Sciences, 3-18-15 Kuramoto-cho, Tokushima, Japan

Abstract

Owing to the surface plasmon resonance-enhanced electromagnetic field, clustered gold nanoparticles–fluorescent silica core–shell nanoparticles became excited within the therapeutic window and fluoresced strongly in this window. The nanoparticles enabled tumor detection using fluorescence imaging and X-ray computed tomography.

Graphical abstract: Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC41876F
Article type
Communication
Submitted
13 Mar 2013
Accepted
22 Apr 2013
First published
23 Apr 2013

Chem. Commun., 2013,49, 5334-5336

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Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors

K. Hayashi, M. Nakamura, H. Miki, S. Ozaki, M. Abe, T. Matsumoto and K. Ishimura, Chem. Commun., 2013, 49, 5334 DOI: 10.1039/C3CC41876F

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