Issue 33, 2013
From the journal:

Chemical Communications

Development of a “signal-on” electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection†

Yao Wua  and  Rebecca Y. Lai*a  

* Corresponding authors

a Department of Chemistry, University of Nebraska-Lincoln, Lincoln, USA
E-mail: rlai2@unl.edu
Fax: +1 402-472-9402
Tel: +1 402-472-5340

Abstract

We report a reagentless and reusable “signal-on” electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.

Graphical abstract: Development of a “signal-on” electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection

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Article information

DOI
https://doi.org/10.1039/C3CC41281D
Article type
Communication
Submitted
19 Feb 2013
Accepted
05 Mar 2013
First published
05 Mar 2013

Chem. Commun., 2013,49, 3422-3424

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Development of a “signal-on” electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection

Y. Wu and R. Y. Lai, Chem. Commun., 2013, 49, 3422 DOI: 10.1039/C3CC41281D

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