Issue 28, 2013
From the journal:

Chemical Communications

Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices†

Zaifang Zhu,a   Lei Liu,b   Wei Wang,a   Joann J. Lu,a   Xiayan Wang*b  and  Shaorong Liu*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA
E-mail: shaorong.liu@ou.edu
Fax: +1 405 325 6111
Tel: +1 405 325 6111

b Department of Chemistry and Chemical Engineering, Beijing University of Technology, Beijing 100124, China
E-mail: xiayanwang@bjut.edu.cn
Fax: +86 106 739 6158
Tel: +86 187 1010 3603

Abstract

We report a novel approach for effectively separating DNA molecules in free solution. The method uses a bare narrow open capillary without any sieving matrices to resolve a wide size-range of DNA fragments at efficiencies of more than a million plates per meter routinely.

Graphical abstract: Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices

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Article information

DOI
https://doi.org/10.1039/C3CC40728D
Article type
Communication
Submitted
28 Jan 2013
Accepted
25 Feb 2013
First published
25 Feb 2013

Chem. Commun., 2013,49, 2897-2899

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Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices

Z. Zhu, L. Liu, W. Wang, J. J. Lu, X. Wang and S. Liu, Chem. Commun., 2013, 49, 2897 DOI: 10.1039/C3CC40728D

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