Issue 8, 2013
From the journal:

Chemical Communications

A kinetic method for expeditious detection of pyrophosphate anions at nanomolar concentrations based on a nucleic acid fluorescent sensor†

Xin Su,a   Chen Zhang,a   Xianjin Xiao,a   Anqin Xu,a   Zhendong Xua  and  Meiping Zhao*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
E-mail: mpzhao@pku.edu.cn
Fax: +86 10-62751708

Abstract

A kinetic method has been developed for highly sensitive and selective detection of pyrophosphate anions (PPi) by using a fluorophore labelled single-stranded-DNA–Al(III) complex system. The facile and spectrum-tunable fluorescent sensor enables rapid detection of PPi in urine and cell lysate solutions without the need for complex pre-cleanup procedures.

Graphical abstract: A kinetic method for expeditious detection of pyrophosphate anions at nanomolar concentrations based on a nucleic acid fluorescent sensor

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Article information

DOI
https://doi.org/10.1039/C2CC38020J
Article type
Communication
Submitted
06 Nov 2012
Accepted
03 Dec 2012
First published
04 Dec 2012

Chem. Commun., 2013,49, 798-800

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A kinetic method for expeditious detection of pyrophosphate anions at nanomolar concentrations based on a nucleic acid fluorescent sensor

X. Su, C. Zhang, X. Xiao, A. Xu, Z. Xu and M. Zhao, Chem. Commun., 2013, 49, 798 DOI: 10.1039/C2CC38020J

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