Issue 9, 2013
From the journal:

Chemical Communications

Catalytic highly enantioselective vinylogous Povarov reaction†

Lorenzo Caruana,a   Mariafrancesca Fochi,*a   Silvia Ranieri,a   Andrea Mazzantia  and  Luca Bernardi*a  

* Corresponding authors

a Department of Industrial Chemistry “Toso Montanari”, School of Science, University of Bologna, V. Risorgimento 4, 40136 Bologna, Italy
E-mail: mariafrancesca.fochi@unibo.it, luca.bernardi2@unibo.it
Fax: +39 051 2093654
Tel: +39 0512093653

Abstract

The first example of a catalytic asymmetric vinylogous Povarov reaction is presented. 1-N-Acylamino-1,3-butadienes react selectively at their terminal double bond in the presence of a chiral phosphoric acid catalyst, delivering highly enantioenriched 1,2,3,4-tetrahydroquinolines bearing a synthetically versatile enecarbamate group at the 4-position.

Graphical abstract: Catalytic highly enantioselective vinylogous Povarov reaction

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC38002A
Article type
Communication
Submitted
05 Nov 2012
Accepted
06 Dec 2012
First published
07 Dec 2012

Chem. Commun., 2013,49, 880-882

Permissions

Request permissions

Catalytic highly enantioselective vinylogous Povarov reaction

L. Caruana, M. Fochi, S. Ranieri, A. Mazzanti and L. Bernardi, Chem. Commun., 2013, 49, 880 DOI: 10.1039/C2CC38002A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements