Issue 3, 2013
From the journal:

Chemical Communications

Arylation of 2-substituted pyridinesvia Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid†

Xinjian Li,ab   Dapeng Zou,ab   Faqiang Leng,ab   Chunxia Sun,ab   Jingya Li,b   Yangjie Wu*a  and  Yusheng Wu*bc  

* Corresponding authors

a The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, PR China
E-mail: wyj@zzu.edu.cn
Tel: +86 371 6776 7993

b Tetranov Biopharm, LLC, 75 Daxue Road, Zhengzhou, PR China

c Tetranov International, Inc. 100 Jersey Avenue, Suite A340, New Brunswick, NJ 08901, USA
E-mail: yusheng.wu@tetranovglobal.com
Fax: +1 732 253 7327
Tel: +1 732 253 7326

Abstract

The novel palladium-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid with aryl and heteroaryl bromides including benzenes, naphthalenes, pyridines and quinolines for C–C bond formation have been successfully achieved.

Graphical abstract: Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid

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Article information

DOI
https://doi.org/10.1039/C2CC36720C
Article type
Communication
Submitted
15 Sep 2012
Accepted
09 Nov 2012
First published
09 Nov 2012

Chem. Commun., 2013,49, 312-314

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Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid

X. Li, D. Zou, F. Leng, C. Sun, J. Li, Y. Wu and Y. Wu, Chem. Commun., 2013, 49, 312 DOI: 10.1039/C2CC36720C

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