Issue 21, 2013
From the journal:

Analytical Methods

A microarray-based resonance light scattering assay for detecting thrombin generation in human plasma by gold nanoparticle probes†

Min Su,ab   Lan Ma,ab   Tao Li,*a   Dianjun Liua  and  Zhenxin Wang*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China
E-mail: wangzx@ciac.ac.cn, litao@ciac.ac.cn
Fax: +86-431-85262243

b University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, P. R. China

Abstract

A peptide microarray-based resonance light scattering (RLS) assay with gold nanoparticle probes has been developed for monitoring thrombin generation in human plasma. Thrombophilia, hypocoagulability and normal plasma have been successfully differentiated by the assay.

Graphical abstract: A microarray-based resonance light scattering assay for detecting thrombin generation in human plasma by gold nanoparticle probes

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Article information

DOI
https://doi.org/10.1039/C3AY41367E
Article type
Communication
Submitted
09 Aug 2013
Accepted
03 Sep 2013
First published
05 Sep 2013

Anal. Methods, 2013,5, 5895-5898

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A microarray-based resonance light scattering assay for detecting thrombin generation in human plasma by gold nanoparticle probes

M. Su, L. Ma, T. Li, D. Liu and Z. Wang, Anal. Methods, 2013, 5, 5895 DOI: 10.1039/C3AY41367E

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