Issue 16, 2013
From the journal:

Analytical Methods

Nanoparticle modified QCM-based sensor for lipase activity determination

Margarita Stoytcheva,a   Roumen Zlatev,*a   Zdravka Velkovab  and  Gisela Monteroa  

* Corresponding authors

a Universidad Autónoma de Baja California, Instituto de Ingeniería, Blvd. B. Juárez s/n, Mexicali, México
E-mail: roumen@uabc.edu.mx
Fax: +52 686 566 4150
Tel: +52 686 566 4150

b Medical University of Plovdiv, Dep. of Chemistry and Biochemistry, Blvd. V. Aprilov 15a, Plovdiv, Bulgaria

Abstract

A highly sensitive lipase activity sensor was developed and tested. It is based on the application of SiO2 nanoparticle loaded olive oil as a lipase substrate, deposited on a QCM crystal. The heavier nanoparticles’ release during the substrate enzymatic degradation causes a QCM frequency response enhancement proportional to the nanoparticle/substrate mass ratio.

Graphical abstract: Nanoparticle modified QCM-based sensor for lipase activity determination

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Article information

DOI
https://doi.org/10.1039/C3AY41047A
Article type
Communication
Submitted
25 Jun 2013
Accepted
27 Jun 2013
First published
27 Jun 2013

Anal. Methods, 2013,5, 3811-3815

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Nanoparticle modified QCM-based sensor for lipase activity determination

M. Stoytcheva, R. Zlatev, Z. Velkova and G. Montero, Anal. Methods, 2013, 5, 3811 DOI: 10.1039/C3AY41047A

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