Issue 15, 2013
From the journal:

Analytical Methods

Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide†

Yinhuan Song,a   Taoyi Yang,a   Tonghuan Zhang,a   Nan Jin,a   Yanjun Zhaoa  and  Aiping Fan*a  

* Corresponding authors

a Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, People's Republic of China
E-mail: fanap@tju.edu.cn
Fax: +86-22-87440581
Tel: +86-22-87440581

Abstract

Graphene oxide (GO) was for the first time designed as a bionanolabel for sensitive chemiluminescent (CL) immunosensing of human IgG by taking advantage of a magnetic separation–mixing process and a GO-triggered luminol–H2O2 CL reaction. The detection limit of the concentration of human IgG is 1.2 pg mL−1, which is comparable with or better than other immunoassays.

Graphical abstract: Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide

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Article information

DOI
https://doi.org/10.1039/C3AY40737C
Article type
Communication
Submitted
03 May 2013
Accepted
09 Jun 2013
First published
10 Jun 2013

Anal. Methods, 2013,5, 3646-3649

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Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide

Y. Song, T. Yang, T. Zhang, N. Jin, Y. Zhao and A. Fan, Anal. Methods, 2013, 5, 3646 DOI: 10.1039/C3AY40737C

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