Issue 7, 2013
From the journal:

Analytical Methods

Electrochemical determination of glutathione based on an electrodeposited nickel oxide nanoparticles-modified glassy carbon electrode

Baiqing Yuan,*a   Xiaoying Zeng,ab   Dehua Deng,a   Chunying Xu,a   Lin Liu,a   Jiayu Zhang,a   Yan Gaoa  and  Huan Pang*ac  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China
E-mail: baiqingyuan1981@126.com, huanpangchem@hotmail.com
Tel: +86 0372 2900040

b School of Pharmaceutical Science, Zhengzhou University, Zhengzhou 450001, Henan, China

c State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing, Jiangsu 210093, China

Abstract

An electrodeposited nickel oxide nanoparticles (NiONPs)-modified glassy carbon (GC) electrode is presented for the first time and used for electrochemical determination of glutathione (GSH). The NiONPs/GC electrode showed a low oxidation potential toward GSH and a wide linear range for its analysis. Different forms of nickel oxide, electrochemically synthesized in different pH buffer solutions, were investigated for the electrochemical oxidation of GSH. The presented sensor was also applied in the analysis of GSH in the presence of uric acid (UA). In addition, the effects of other interfering species including ascorbic acid (AA), dopamine (DA) and glucose were examined and discussed in detail.

Graphical abstract: Electrochemical determination of glutathione based on an electrodeposited nickel oxide nanoparticles-modified glassy carbon electrode

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Article information

DOI
https://doi.org/10.1039/C3AY26536F
Article type
Paper
Submitted
12 Dec 2012
Accepted
05 Feb 2013
First published
05 Feb 2013

Anal. Methods, 2013,5, 1779-1783

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Electrochemical determination of glutathione based on an electrodeposited nickel oxide nanoparticles-modified glassy carbon electrode

B. Yuan, X. Zeng, D. Deng, C. Xu, L. Liu, J. Zhang, Y. Gao and H. Pang, Anal. Methods, 2013, 5, 1779 DOI: 10.1039/C3AY26536F

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