Issue 13, 2013
From the journal:

Analyst

Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device†

James A. Richardson,a   Trevor Morgan,b   Michael Andreoub  and  Tom Brown*a  

* Corresponding authors

a Chemistry, University of Southampton, Southampton, Hampshire, UK
E-mail: tb2@soton.ac.uk
Fax: +44 (0)23 8059 2991
Tel: +44 (0)23 8059 2974

b OptiGene Ltd, Unit 5 Blatchford Road, Horsham, West Sussex, UK
E-mail: Michael@optigene.co.uk
Fax: +44 (0)1403 271017
Tel: +44 (0)1403 274980

Abstract

The intense demand for fluorescence-based point of care (POC) DNA diagnostics is driving developments to reduce the size of instrumentation, imposing limitations on the optical hardware that can be included. Here we describe a combination of instrumentation and fluorogenic probes to detect three fluorophores using two excitation and two detection channels.

Graphical abstract: Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3AN00593C
Article type
Communication
Submitted
26 Mar 2013
Accepted
08 May 2013
First published
09 May 2013

Analyst, 2013,138, 3626-3628

Permissions

Request permissions

Use of a large Stokes-shift fluorophore to increase the multiplexing capacity of a point-of-care DNA diagnostic device

J. A. Richardson, T. Morgan, M. Andreou and T. Brown, Analyst, 2013, 138, 3626 DOI: 10.1039/C3AN00593C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements