Issue 38, 2012
From the journal:

Soft Matter

Analysis of native structures of soft materials by cryo scanning probe tomography†

Anton E. Efimov,*a   Helmut Gnaegi,b   Raimund Schaller,c   Werner Grogger,de   Ferdinand Hoferde  and  Nadejda B. Matsko*e  

* Corresponding authors

a Laboratory of Bionanotechnology, V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs, Shchukinskaya str., 1, Moscow, 123182 Russia
E-mail: antefimov@gmail.com
Tel: +7 9161642475

b Diatome Ltd, P.O. Box, Biel-Bienne, CH-2501 Switzerland
E-mail: helmut.gnaegi@diatome.ch
Fax: +41 323315257
Tel: +41 323329113

c Semperit Technische Produkte GmbH, Triester Bundesstraße 26, Wimpassing, A-2632 Austria
E-mail: Raimund.Schaller@semperit.at
Fax: +43 2630310479
Tel: +43 26303100

d Institute for Electron Microscopy and Fine Structural Research, Graz University of Technology, Steyrergasse, 17, Graz, Austria
E-mail: werner.grogger@felmi-zfe.at, ferdinand.hofer@felmi-zfe.at
Fax: +43 316 811 596
Tel: +43 316 873 8820

e Graz Centre for Electron Microscopy, Steyrergasse, 17, Graz, A-8010 Austria
E-mail: nadejda.matsko@felmi-zfe.at
Fax: +43 316 811596
Tel: +43 316 873-8335

Abstract

We propose a universal tool for structural analysis of soft/frozen-hydrated materials at a macromolecular level over a wide range of temperatures (−120 to +50 °C). The cryogenic scanning probe microscope presented here allows detailed investigation and serial-section 3D tomography of soft matter under native-like conditions.

Graphical abstract: Analysis of native structures of soft materials by cryo scanning probe tomography

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Article information

DOI
https://doi.org/10.1039/C2SM26050F
Article type
Communication
Submitted
05 May 2012
Accepted
02 Aug 2012
First published
22 Aug 2012

Soft Matter, 2012,8, 9756-9760

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Analysis of native structures of soft materials by cryo scanning probe tomography

A. E. Efimov, H. Gnaegi, R. Schaller, W. Grogger, F. Hofer and N. B. Matsko, Soft Matter, 2012, 8, 9756 DOI: 10.1039/C2SM26050F

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