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Issue 33, 2012
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The high stability of intermediate radicals enhances the radical-scavenging activity of aminochromanols

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Abstract

The hydroxyl radical-scavenging activity of the amino-substituted α-tocopherol analogues was much higher than that of α-tocopherol. Aminochromanoxyl radicals generated from 5- and 7-aminochromanol were successfully detected in aqueous solution at room temperature during ESR measurements. The stability of the aminochromanoxyl radicals leads to a significant enhancement of the radical-scavenging activity.

Graphical abstract: The high stability of intermediate radicals enhances the radical-scavenging activity of aminochromanols

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Publication details

The article was received on 24 Aug 2012, accepted on 29 Oct 2012 and first published on 07 Nov 2012


Article type: Communication
DOI: 10.1039/C2RA21928J
Citation: RSC Adv., 2012,2, 12714-12717
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    The high stability of intermediate radicals enhances the radical-scavenging activity of aminochromanols

    K. Inami, I. Nakanishi, M. Morita, M. Furukawa, K. Ohkubo, S. Fukuzumi and M. Mochizuki, RSC Adv., 2012, 2, 12714
    DOI: 10.1039/C2RA21928J

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