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Issue 26, 2012
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Chemistry with spatial control using particles and streams

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Spatial control of chemical reactions, with micro- and nanometer scale resolution, has important consequences for one pot synthesis, engineering complex reactions, developmental biology, cellular biochemistry and emergent behavior. We review synthetic methods to engineer this spatial control using chemical diffusion from spherical particles, shells and polyhedra. We discuss systems that enable both isotropic and anisotropic chemical release from isolated and arrayed particles to create inhomogeneous and spatially patterned chemical fields. In addition to such finite chemical sources, we also discuss spatial control enabled with laminar flow in 2D and 3D microfluidic networks. Throughout the paper, we highlight applications of spatially controlled chemistry in chemical kinetics, reaction-diffusion systems, chemotaxis and morphogenesis.

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The article was received on 23 Feb 2012, accepted on 01 Jul 2012 and first published on 03 Jul 2012

Article type: Review Article
DOI: 10.1039/C2RA20337E
Citation: RSC Adv., 2012,2, 9707-9726
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    Chemistry with spatial control using particles and streams

    Y. V. Kalinin, A. Murali and D. H. Gracias, RSC Adv., 2012, 2, 9707
    DOI: 10.1039/C2RA20337E

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