Jump to main content
Jump to site search

Issue 3, 2012
Previous Article Next Article

ZnO/Ag nanohybrid: synthesis, characterization, synergistic antibacterial activity and its mechanism

Author affiliations

Abstract

A highly homogeneous ZnO/Ag nanohybrid has been synthesized by a novel route, employing chitosan as mediator by purely electrostatic interaction. By employing various techniques such as powder XRD, UV-visible, IR spectroscopy and electron (SEM, TEM) microscopy, the formation of the nanohybrid has been established. The synergistic antibacterial effect of ZnO/Ag nanohybrid on Gram-positive and Gram-negative bacteria is found to be more effective, compared to the individual components (ZnO and Ag). Cytotoxicity experiments are carried out and the results are correlated to the solubility of the nanohybrid. A possible mechanism has been proposed for the antibacterial activity of ZnO/Ag nanohybrid, based on TEM studies on bacteria, carried out by employing the microtome technique and by EPR measurements on the hybrid.

Graphical abstract: ZnO/Ag nanohybrid: synthesis, characterization, synergistic antibacterial activity and its mechanism

Back to tab navigation

Supplementary files

Article information


Submitted
29 Sep 2011
Accepted
04 Oct 2011
First published
28 Nov 2011

RSC Adv., 2012,2, 930-940
Article type
Paper

ZnO/Ag nanohybrid: synthesis, characterization, synergistic antibacterial activity and its mechanism

S. Ghosh, V. S. Goudar, K. G. Padmalekha, S. V. Bhat, S. S. Indi and H. N. Vasan, RSC Adv., 2012, 2, 930
DOI: 10.1039/C1RA00815C

Social activity

Search articles by author

Spotlight

Advertisements