Issue 12, 2012
From the journal:

RSC Advances

An efficient pyrroline annulation of glycine imine with enones†

Yu Zhang,a   Ling Pan,*a   Xianxiu Xua  and  Qun Liu*a  

* Corresponding authors

a Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, China
E-mail: panl948@nenu.edu.cn, liuqun@nenu.edu.cn
Fax: +86-431-85099759
Tel: +86-431-85099759

Abstract

We describe here a single-step synthesis of substituted 1-pyrrolines from N-(4-chlorobenzylidene)-glycine methyl ester and enones which combines conversion of the Michael adducts to 1-pyrrolines with separation between the products on silica gel column chromatography.

Graphical abstract: An efficient pyrroline annulation of glycine imine with enones

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Article information

DOI
https://doi.org/10.1039/C2RA20697H
Article type
Communication
Submitted
18 Apr 2012
Accepted
19 Apr 2012
First published
17 May 2012

RSC Adv., 2012,2, 5138-5140

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An efficient pyrroline annulation of glycine imine with enones

Y. Zhang, L. Pan, X. Xu and Q. Liu, RSC Adv., 2012, 2, 5138 DOI: 10.1039/C2RA20697H

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