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Issue 3, 2012
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Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis

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Abstract

Caged non-ionic detergents, comprised of polar oligo(ethylene glycol) and non-polar alkyl chains joined by a photocleavable ortho-nitrobenzyl sulfonate linker have been synthesized and characterized. The light-triggered transformation of such chameleon surfactant from a charge-neutral into a charged form offers great potential to improve 2-D gel electrophoretic separation of complex protein mixtures.

Graphical abstract: Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis

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Publication details

The article was received on 27 Sep 2011, accepted on 14 Nov 2011 and first published on 05 Jan 2012


Article type: Communication
DOI: 10.1039/C1PP05316G
Photochem. Photobiol. Sci., 2012,11, 497-499

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    Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis

    O. Bogen, P. Milosevic, H. Daroszi, M. Dreger, S. Hecht and F. Hucho, Photochem. Photobiol. Sci., 2012, 11, 497
    DOI: 10.1039/C1PP05316G

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