Issue 3, 2012
From the journal:

Photochemical & Photobiological Sciences

Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis†‡

Oliver Bogen,a   Petar Milosevic,b   Hans Daroszi,a   Mathias Dreger,a   Stefan Hecht*bc  and  Ferdinand Hucho*a  

* Corresponding authors

a Institut für Chemie - Biochemie, Freie Universität Berlin, Thielallee 63, Berlin, Germany
E-mail: hucho@chemie.fu-berlin.de

b Institut für Chemie – Organische Chemie, Freie Universität Berlin, Takustr., 3, Berlin, Germany

c Department of Chemistry, Humboldt-Universität zu Berlin, Germany
E-mail: sh@chemie.hu-berlin.de
Fax: +49 30 2093-6940
Tel: +49 30 2093-7365

Abstract

Caged non-ionic detergents, comprised of polar oligo(ethylene glycol) and non-polar alkyl chains joined by a photocleavable ortho-nitrobenzyl sulfonate linker have been synthesized and characterized. The light-triggered transformation of such chameleon surfactant from a charge-neutral into a charged form offers great potential to improve 2-D gel electrophoretic separation of complex protein mixtures.

Graphical abstract: Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis

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Article information

DOI
https://doi.org/10.1039/C1PP05316G
Article type
Communication
Submitted
27 Sep 2011
Accepted
14 Nov 2011
First published
05 Jan 2012

Photochem. Photobiol. Sci., 2012,11, 497-499

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Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis

O. Bogen, P. Milosevic, H. Daroszi, M. Dreger, S. Hecht and F. Hucho, Photochem. Photobiol. Sci., 2012, 11, 497 DOI: 10.1039/C1PP05316G

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