Issue 1, 2012

Synthesis of α,β-unsaturated γ-amino esters with a quaternary center by ruthenium-catalyzed codimerization of N-acetyl α-arylenamines and acrylates

Abstract

Ruthenium-catalyzed highly selective codimerization of N-acetyl α-arylenamines with ethyl acrylates is reported. This codimerization reaction provides a new efficient method for the synthesis of α,β-unsaturated γ-amino esters with a quaternary center.

Graphical abstract: Synthesis of α,β-unsaturated γ-amino esters with a quaternary center by ruthenium-catalyzed codimerization of N-acetyl α-arylenamines and acrylates

Supplementary files

Article information

Article type
Communication
Submitted
18 Aug 2011
Accepted
09 Sep 2011
First published
09 Sep 2011

Org. Biomol. Chem., 2012,10, 43-45

Synthesis of α,β-unsaturated γ-amino esters with a quaternary center by ruthenium-catalyzed codimerization of N-acetyl α-arylenamines and acrylates

Q. Wang, J. Xie, L. Guo and Q. Zhou, Org. Biomol. Chem., 2012, 10, 43 DOI: 10.1039/C1OB06412F

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