Issue 7, 2013

Au(i)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide

Abstract

We have developed gold(I)-catalyzed oxidative cyclopropanation of 1,6-enynes derived from propiolamides employing diphenyl sulfoxide as an oxidant. 1,6-Enynes having a terminal alkyne and a propiolamide tether efficiently transformed into cyclopropane carboxaldehyde derivatives.

Graphical abstract: Au(i)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide

Supplementary files

Article information

Article type
Communication
Submitted
10 Dec 2012
Accepted
21 Dec 2012
First published
02 Jan 2013

Org. Biomol. Chem., 2013,11, 1089-1092

Au(I)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide

H. Yeom and S. Shin, Org. Biomol. Chem., 2013, 11, 1089 DOI: 10.1039/C2OB27394B

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