Issue 45, 2012
From the journal:

Organic & Biomolecular Chemistry

Synthesis and properties of squaraine-modified DNA†

Larysa I. Markova,ab   Vladimir L. Malinovskii,a   Leonid D. Patsenkerb  and  Robert Häner*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland
E-mail: robert.haener@ioc.unibe.ch
Tel: (+)41 31 631 4382

b Department of Organic Luminophores and Dyes, State Scientific Institution “Institute for Single Crystals” of the National Academy of Sciences of Ukraine, 60, Lenin Ave., Kharkiv 61001, Ukraine
E-mail: patsenker@isc.kharkov.com
Fax: +38 (057) 340-02-73
Tel: +38 (057) 341-02-72

Abstract

The incorporation of squaraines into DNA via the phosphoramidite approach is described. High molar absorptivity, environment-sensitive fluorescence properties and intense CD effects render squaraines valuable building blocks for DNA-based optical probes and nanostructures.

Graphical abstract: Synthesis and properties of squaraine-modified DNA

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Article information

DOI
https://doi.org/10.1039/C2OB26787J
Article type
Communication
Submitted
11 Sep 2012
Accepted
02 Oct 2012
First published
02 Oct 2012

Org. Biomol. Chem., 2012,10, 8944-8947

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Synthesis and properties of squaraine-modified DNA

L. I. Markova, V. L. Malinovskii, L. D. Patsenker and R. Häner, Org. Biomol. Chem., 2012, 10, 8944 DOI: 10.1039/C2OB26787J

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