Evaluation of a 125I-labelled benzazepinone derived voltage-gated sodium channel blocker for imaging with SPECT†
Abstract
Voltage-gated sodium channels (VGSCs) are a family of transmembrane
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* Corresponding authors
a
Department of Chemistry and Institute of Nuclear Medicine, UCL, 235 Euston Road (T-5), NW1 2BU London, United Kingdom
E-mail:
e.arstad@ucl.ac.uk
Fax: +44 (0)02076792344
Tel: +44 (0)02076792344
b Centre for Advanced Biomedical Imaging, Department of Medicine and UCL Institute of Child Health, 72 Huntley Street, WC1E 6DD London, United Kingdom
c Tumour Biology Section, UCL Cancer Institute, 72 Huntley Street, London, United Kingdom
Voltage-gated sodium channels (VGSCs) are a family of transmembrane
C. Pérez-Medina, N. Patel, M. Robson, A. Badar, M. F. Lythgoe and E. Årstad, Org. Biomol. Chem., 2012, 10, 9474 DOI: 10.1039/C2OB26695D
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